Zoellner Medical Group
Tulsa First-class Medical Care
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Ketamine infusion therapy is an innovative and fast-acting treatment for those affected by anxiety, depression, mood disorders, chronic migraines, pain and other similar disorders.

Patients with these issues do not always respond to oral antidepressants or other therapy. The good news is that Ketamine infusion therapy has emerged as an effective treatment option for many patients suffering from treatment resistant depression.

Ketamine is given as a low dose infusion and works differently from other currently available medication by blocking a neurotransmitter in the brain called glutamate. Research goes on to fully understand the effects of blocking the glutamate (NMDA) receptor, but it appears that neuron connection damage caused by “being depressed” is reversed allowing for healthy connections to develop. The result is a dramatic and rapid improvement in severe depression.

Patients with mild depression, situational depression, or mood swings are not candidates for Ketamine infusion therapy.


Ketamine Therapy Overview

Ketamine is a medication that has been prescribed to men, women and children mainly as an anesthetic, since the early 1960s. In 2000, researchers discovered that ketamine has a tremendous effect on depression, especially for those patients resistant to treatments with typical antidepressants.

Since then, doctors have seen continuous - and powerful- results of ketamine treatment through continued research and treatments. These improvements include a boost in mood almost immediately and none of the side effects typically seen with classic antidepressants. Around 70% of ketamine treatment patients experience an improvement in symptoms and can continue protocol for ketamine infusions.

How Does the Treatment Work?

Zoellner Medical Group provides private infusion areas for each patient. All patients can have a friend or family member present during therapy if they so choose. Patients will have their vital signs continuously monitored by qualified medical professionals and an anesthesiologist will be available at all times. Some patients prefer to listen to music on their headphones, read or take a nap.

Once the IV is started, each ketamine infusion lasts 30-45 minutes. During the infusion, a variety of sensations may occur including dream-like sensations, euphoria, light and sound sensitivity or blurring of vision. Some patients may experience headache, nausea or sometimes elevated blood pressure. Should this occur, medication will be readily available for treatment. Once ketamine therapy has stopped, patients will have a short recovery period, during which they will notice a rapid reduction in any symptoms. The entire process takes around 90 minutes. Once the infusion is complete, patients will need a ride home since they feel dizzy or light-headed.

Ketamine Therapy Costs

  • Evaluation/Screening: $1500 (includes evaluation, first 3 infusions, and mood reassessment) The typical response occurs within 4-24 hours, with the maximum effect seen the third day after each infusion. In some cases, some people do not feel an improvement in mood until after their third infusion. This is not abnormal. ZMG will reassess your mood after three infusions.

  • Next three infusions: $1500 total (required to maximize the effect and postpone recurrence most effectively) All 6 infusions take place within 3-4 weeks.

  • Maintenance infusion: $500 each (no more than one infusion per month) The average maintenance infusion is every 2-4 months.

Please note...ketamine infusions are not currently covered by insurance at this time.